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Search Results for " interferon β "

Targets Recommended: IFNAR

24

抑制剂 & 化合物

3

天然产物

60

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T13736	Interferon receptor inducer-1	IFNAR	Immunology/Inflammation
	Interferon receptor inducer-1 是一种干扰素(IFN)受体诱导剂，可用于干扰素诱导参与的紊乱性疾病的研究。
T12933	SM-276001	TLR; COX	Immunology/Inflammation; Neuroscience
	SM-276001 是可口服的干扰素诱导剂，是选择性TLR7激动剂，可以诱导抗肿瘤免疫反应。
T8798	MSA-2	STING	Immunology/Inflammation
	MSA-2 是可口服的非核苷酸 STING 激动剂，以具有纳摩尔亲和力的非共价二聚体形式与 STING 结合。它在同基因小鼠肿瘤模型中显示抗肿瘤活性，与抗 PD-1 协同作用，可刺激肿瘤分泌干扰素-β，诱导肿瘤消退，具有持久的抗肿瘤免疫。
T14687	Deucravacitinib BMS-986165	Tyrosine Kinases; JAK; IFNAR; Interleukin	Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	Deucravacitinib (BMS-986165) 是一种高选择性、口服生物可利用的变构 TYK2 抑制剂，用于治疗自身免疫性疾病。它通过稳定调节 JH2 结构域来阻断受体介导的 Tyk2 激活，可抑制IL-12/23和 I 型IFN 途径。它选择性结合 TYK2 假激酶 (JH2) 结构域，IC50为1.0 nM。
T11630	IFN alpha-IFNAR-IN-1 hydrochloride	Others; IFNAR	Immunology/Inflammation; Others
	IFN alpha-IFNAR-IN-1 hydrochloride 是 IFN-α 和 IFNAR 相互作用的抑制剂。 IFN alpha-IFNAR-IN-1 hydrochloride 抑制 BM-pDCs 的 MVA 诱导的 IFN-α 反应，IC50 为 2-8 μM。
T7081	CCCP Carbonyl Cyanide m-Chlorophenylhydrazone,Carbonyl cyanide 3-chlorophenylhydrazone,羰基氰化氯苯腙	Apoptosis; IκB/IKK; COX; Mitochondrial Metabolism; STING; IFNAR; Antibacterial	Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; NF-κB
	CCCP (Carbonyl Cyanide m-Chlorophenylhydrazone) 是一种氧化磷酸化 (OXPHOS) 抑制剂，线粒体质子载体解偶联剂。CCCP 抑制 STING 及其下游信号分子 TBK1 和 IRF3 的激活。
T5317	Cridanimod CMA,吖啶酮乙酸,XBIO-101,10-carboxymethyl-9-acridanone	Progesterone Receptor; STING; IFNAR	Immunology/Inflammation; Others
	Cridanimod (10-carboxymethyl-9-acridanone, CMA) 是一种是小分子免疫调节剂和干扰素诱导剂，是一种孕酮受体激活剂，能够诱导 IFNα和IFNβ的表达，显著增加 PR 的表达。
T4403	AX-024 hydrochloride AX-024 HCl	IL Receptor; TNF; COX; IFNAR; Interleukin	Apoptosis; Immunology/Inflammation; Neuroscience
	AX-024 hydrochloride (AX-024 HCl) 是一种细胞因子释放抑制剂，可强烈抑制 IL-6、TNFα、IFN-γ、IL-10 和 IL-17A 的产生。它是口服可利用的 TCR-Nck 相互作用抑制剂，可选择性地抑制 TCR 触发的 T 细胞活化。它通过靶向 SH3结构域调节细胞信号传导，具有低毒、高效和高选择性的特点。
T22142	RO8191 RO4948191,CDM-3008	HCV Protease; HBV; JAK; IFNAR; STAT	Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells
	RO8191 (CDM-3008) 是干扰素 (IFN) 受体激动剂。它直接与 IFNα/β 受体 2 结合，激活 IFN 刺激的基因表达和 JAK/STAT 磷酸化。它通过具有干扰素样活性发挥 cccDNA 调节剂作用，并具有抗 HBV 活性。
T6273	Vadimezan DMXAA,伐地美生,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404	Influenza Virus; VDA; STING; IFNAR	Angiogenesis; Immunology/Inflammation; Microbiology/Virology
	Vadimezan (DMXAA) 是一种血管破坏剂，一种鼠 STING 激动剂，也是一种细胞因子如 I 型 IFN 的诱导剂。Vadimezan 具有抗肿瘤活性，可以诱导肿瘤中的血流快速停止，但不影响正常组织中的血流。
T77038	Interferon alfa
	Interferon alfa 是 I 型干扰素，可激活新基因，对靶细胞产生有效抗病毒和抗增殖活性。Interferon alfa 的信号传导需要 Stat1和 Stat2 的受体依赖性激活，形成异源二聚化 STAT。STAT 复合物与 DNA 结合蛋白 IRF-9 (p48) 结合并形成 ISGF-3 (IFN 刺激基因因子 3)。随后由 ISGF-3 进一步激活驱动基因，实现抗病毒功能。
T26895	BRD0476 BRD-0476,ML 187,ML187,ML-187,BRD 0476
	BRD0476 is a suppressor of pancreatic β-cell apoptosis. BRD0476 inhibits interferon-gamma (IFN-γ)-induced Janus kinase 2 (JAK2) and signal transducer and activation of transcription 1 (STAT1) signaling to promote β-cell survival. BRD0476 inhibits JAK-STAT
T38162	STING18
	STING18 is a competitive ligand of stimulator of interferon genes (STING; IC50 = 0.068 μM in a radioligand binding assay).1 It inhibits cGAMP-induced IFN-β production (IC50 = 11 μM) but does not stimulate IFN-β production (EC50 = >30 μM) in THP-1 cells. \|1. Siu, T., Altman, M.D., Baltus, G.A., et al. Discovery of a novel cGAMP competitive ligand of the inactive form of STING. Med. Chem. Lett. 10(1), 92-97 (2019).
T76930	Bifarcept
	Bifarcept为一种针对干扰素受体I型(IFN-RI)的重组抗体，能与IFN-β结合，从而延长其在血清中的半衰期。
T35654	2'2'-cGAMP (sodium salt)
	2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds. It binds to the adapter protein stimulator of interferon genes , which is a component of the innate immune response that activates the type I interferon pathway when bound to cyclic dinucleotides. 2'2-cGAMP shows weaker binding to STING than 2'3'-cGAMP but binds more strongly than 3'3'-cGAMP , cyclic di-GMP , or 3'2'-cGAMP, which bind in the micromolar range (Kds = 1.04, 1.21, or 1.61 μM, respecti...
T10065	2',3'-cGAMP 2'-3'-cyclic GMP-AMP	STING; cGAS	Immunology/Inflammation
	2',3'-cGAMP (2'-3'-cyclic GMP-AMP) 是细胞天然免疫中第二信使，在DNA结合条件下由 cGAMP 合成酶 (cGAS) 催化形成。2',3'-cGAMP 可与 STING 结合形成二聚体，诱导干扰素-β（IFN-β）及其他细胞因子的产生和表达。
T73693	Peginterferon beta-1a
	Peginterferon beta-1a (Peginterferon β-1a) 是一个聚乙二醇化干扰素 beta-1a 分子。Peginterferon beta-1a 诱导癌细胞凋亡并且在裸鼠模型中显示出抗肿瘤活性。Peginterferon beta-1a 可用于癌症和多发性硬化 (RMS) 的研究。
T38091	3'3'-cGAMP (sodium salt)
	3'3'-cGAMP is a second messenger produced in bacteria by specific dinucleotide cyclases. It contains canonical 3'5'-phosphodiester bonds and regulates chemotaxis, colonization, and other cellular functions. 3'3'-cGAMP shows weaker binding to the adapter protein stimulator of interferon genes (STING; Kd = 1.04 μM) than 2'2'-cGAMP and 2'3'-cGAMP but has similar binding affinity to 3'2'-cGAMP (Kd = 1.61 μM) and cyclic di-GMP . 3'3'-cGAMP induces IFN-β mRNA expression in L929 cells (EC50 = 40.5 nM).
T38160	STING Agonist 1a
	STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expression of IFN-β, IL-6, and chemokine (C-X-C motif) ligand 10 (CXCL10) in THP-1 cells, an effect that can be reversed by STING knockout or the STING inhibitor H-151 . 1.Hou, H., Yang, R., Liu, X., et al.Discovery of triazoloquinoxaline as novel STING agonists via structure-based vir...
T38158	StA-IFN-1
	StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1 , which specifically inhibits the IKKβ component of the IFN induction pathway. It does not show inhibitory activity in a GFP reporter assay for IFN signaling in which ruxolitinib , which is specific for the IFN signaling component JAK1, is active. StA-IFN-1 reduces the levels of IFN-β, but not ISG MxA, mRNA, suggesting that it is selective f...
T36461	CAY10748 CAY10748
	CAY10748 is an agonist of stimulator of interferon genes (STING; IC50= 0.3794 μM in a competition binding assay).1It activates STING in STING-expressing, but not STING knockout, THP-1 cells (EC50s = 0.287 and >100 μM, respectively, in a reporter assay). It induces phosphorylation of STING at the serine in position 366, as well as phosphorylation of TBK1 and IFN regulatory factor 3 (IRF3), indicating activation of the STING-TBK1-IRF3 signaling pathway. CAY10748 increases the secretion of IFN-β an...
T38161	STING Agonist C11 STING Agonist C11
	STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.1 It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 μM. STING agonist C11 induces phosphorylation of IFN regulatory factor 3 (IRF3) and increases expression of IFIT1 and viperin, but not IL-1β, IL-6, or IL-8 in THF cells in a STING-dependent manner. It reduces viral titers of chikungunya, Venezuelan equine encephalitis, o'nyong-nyong, Mayaro, and Ross River viruses gro...
T83841	STING Agonist D61 D61,Stimulator of Interferon Genes Agonist D61
	STING激动剂D61（D61）是干扰素基因刺激剂(STING)的激动剂。它在基于细胞的分析中诱导IFN3诱导的分泌性碱性磷酸酶(SEAP)报告基因和IFN-β诱导的报告基因的表达（EC50分别为52.9和116 nM）。D61（4, 6, 和8 µM）增加了编码IFN-β和化学因子（C-X-C基序）配体10（CXCL10）的mRNA的表达以及TANK结合激酶1（TBK1）、IRF3和STING在THP-1单核细胞中的磷酸化。在体内，D61（每隔一天0.25 mg/kg）在CT26小鼠结肠癌模型中减少肿瘤体积，而不影响体重。
T83775	STING Agonist 12L Stimulator of Interferon Genes Agonist 12L
	STING激动剂12L是一种刺激干扰素基因(STING)的激动剂。它与野生型STING结合(IC50 = 1.15 µM)，以及STING的R232、AQ和Q变体(IC50分别为1.06、0.61和1.12 µM)，并在THP-1和RAW 264.7细胞中诱导报告基因表达(EC50分别为0.38和12.94 µM)。STING激动剂12L (5 µM)在THP-1细胞中诱导IFNB1、CXCL10和IL6 mRNA的表达。在体内，STING激动剂12L (10 mg/kg)提高了血浆IFN-β水平，并且在B16/F10小鼠黑色素瘤模型中减少了肿瘤体积和肺转移灶的数量。

化合物

Interferon receptor inducer-1

Cat.No: T13736

Target: IFNAR

Cat.No: T12933

Target: TLR, COX

Cat.No: T8798

Target: STING

Deucravacitinib

Cat.No: T14687

Synonym: BMS-986165

Target: Tyrosine Kinases, JAK, IFNAR, Interleukin

IFN alpha-IFNAR-IN-1 hydrochloride

Cat.No: T11630

Target: Others, IFNAR

Cat.No: T7081

Synonym: Carbonyl Cyanide m-Chlorophenylhydrazone,Carbonyl cyanide 3-chlorophenylhydrazone,羰基氰化氯苯腙

Target: Apoptosis, IκB/IKK, COX, Mitochondrial Metabolism, STING, IFNAR, Antibacterial

Cat.No: T5317

Synonym: CMA,吖啶酮乙酸,XBIO-101,10-carboxymethyl-9-acridanone

Target: Progesterone Receptor, STING, IFNAR

AX-024 hydrochloride

Cat.No: T4403

Synonym: AX-024 HCl

Target: IL Receptor, TNF, COX, IFNAR, Interleukin

Cat.No: T22142

Synonym: RO4948191,CDM-3008

Target: HCV Protease, HBV, JAK, IFNAR, STAT

Cat.No: T6273

Synonym: DMXAA,伐地美生,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404

Target: Influenza Virus, VDA, STING, IFNAR

Interferon alfa

Cat.No: T77038

Cat.No: T26895

Synonym: BRD-0476,ML 187,ML187,ML-187,BRD 0476

Cat.No: T38162

Cat.No: T76930

2'2'-cGAMP (sodium salt)

Cat.No: T35654

Cat.No: T10065

Synonym: 2'-3'-cyclic GMP-AMP

Target: STING, cGAS

Peginterferon beta-1a

Cat.No: T73693

3'3'-cGAMP (sodium salt)

Cat.No: T38091

STING Agonist 1a

Cat.No: T38160

Cat.No: T38158

Cat.No: T36461

Synonym: CAY10748

STING Agonist C11

Cat.No: T38161

Synonym: STING Agonist C11

STING Agonist D61

Cat.No: T83841

Synonym: D61,Stimulator of Interferon Genes Agonist D61

STING Agonist 12L

Cat.No: T83775

Synonym: Stimulator of Interferon Genes Agonist 12L

Cat. No.	Product Name	Target	Signaling Pathways
T3829	Ginsenoside F3 人参皂苷F3	Others; IFNAR; Interleukin	Immunology/Inflammation; Others
	Ginsenoside F3 是一种皂苷，提取自Panax ginseng 叶片。它能够调节1 型 (IL-2, IFN-γ) 及 2 型细胞因子(IL-4 and IL-10) 的产生和表达，有免疫增强的作用。
T14854	Caerulomycin A 浅蓝霉素,Cerulomycin,Caerulomycin	Antifungal	Microbiology/Virology
	Caerulomycin A (Caerulomycin) 是抗真菌和抗细菌化合物，能够诱导 T 细胞的产生。它能够抑制 IFN-γ 诱导的 STAT1 通路，从而增强 TGF-β-Smad3 信号通路。它可用于自身免疫病的研究。
T10065L	2',3'-cGAMP sodium 2'-3'-cyclic GMP-AMP sodium	STING; cGAS	Immunology/Inflammation
	2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) 是细胞天然免疫中第二信使，在DNA结合条件下由 cGAMP 合成酶 (cGAS) 催化形成。2',3'-cGAMP sodium 可与 STING 结合形成二聚体，诱导干扰素-β（IFN-β）及其他细胞因子的产生和表达。

天然产物

Cat.No: T3829

Synonym: 人参皂苷F3

Target: Others, IFNAR, Interleukin

Cat.No: T14854

Synonym: 浅蓝霉素,Cerulomycin,Caerulomycin

Target: Antifungal

2',3'-cGAMP sodium

Cat.No: T10065L

Synonym: 2'-3'-cyclic GMP-AMP sodium

Target: STING, cGAS

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00831	IFN-beta Protein, Human, Recombinant (hFc) IFNB,IFN-β,Interferon beta,interferon<...	Human	HEK293 Cells
	IFN-beta Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is A0A7R8GV38.
TMPY-03145	IFN-beta Protein, Human, Recombinant IFN-β,interferon, β1, fibroblast,...	Human	CHO Cells
	IFN-beta Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 20 kDa and the accession number is P01574.
TMPY-03467	IFN-beta Protein, Mouse, Recombinant Ifb,IFN-β,interferon, beta 1, fibroblast,干...	Mouse	HEK293 Cells
	IFN-beta Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.3 kDa and the accession number is P01575.
TMPY-02647	IFNAR1 Protein, Human, Recombinant (His) interferon (alpha, beta and omega) receptor 1,IFN-α...	Human	HEK293 Cells
	IFNAR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.6 kDa and the accession number is P17181-1.
TMPY-04799	IFNAR2 Protein, Human, Recombinant (His), Biotinylated IFN-R,interferon (α, β and Ω) receptor 2,I...	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPY-03828	IFN-beta Protein, Rhesus, Recombinant (mFc) interferon, beta 1, fibroblast,干扰素,interferon	Rhesus	HEK293 Cells
	IFN-beta Protein, Rhesus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.4 kDa and the accession number is G7NFX1.
TMPY-04254	IFNAR1 Protein, Rhesus, Recombinant (His) interferon (alpha, beta and omega) receptor 1,i...	Rhesus	HEK293 Cells
	IFNAR1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.7 kDa and the accession number is H9Z8H4.
TMPY-03829	IFNAR1 Protein, Rhesus, Recombinant (hFc) interferon (α, β and Ω) receptor 1,int...	Rhesus	HEK293 Cells
	IFNAR1 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 74.5 kDa and the accession number is H9Z8H4.
TMPY-00139	IFNAR2 Protein, Cynomolgus, Recombinant (His) interferon (α, β and Ω) receptor 2,int...	Cynomolgus	HEK293 Cells
	IFNAR2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is XP_005548871.1.
TMPY-03927	IFNAR1 Protein, Rhesus, Recombinant interferon (α, β and ω) receptor 1,int...	Rhesus	HEK293 Cells
	IFNAR1 Protein, Rhesus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 48.3 kDa and the accession number is H9Z8H4.
TMPY-02456	IFN-beta Protein, Mouse, Recombinant (hFc) Ifb,interferon, β1, fibroblast,IFN-β	Mouse	HEK293 Cells
	IFN-beta Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is P01575.
TMPY-01489	IFNAR1 Protein, Mouse, Recombinant (His) Ifrc,Ifar,CD118,interferon (α, β and ω) re...	Mouse	HEK293 Cells
	IFNAR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is P33896.
TMPY-00007	Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant interferon, alpha 2,Ifa2,interferon, α2,干扰...	Mouse	P. pastoris (Yeast)
	Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant is expressed in yeast. The predicted molecular weight is 19.4 kDa and the accession number is B1AYH7.
TMPY-01640	IFNAR2 Protein, Human, Recombinant (hFc) interferon (α, β and ω) receptor 2,IFNABR,...	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.8 kDa and the accession number is P48551-1.
TMPY-01642	IFNAR2 Protein, Human, Recombinant (His) IFNARB,IFNABR,interferon (α, β and ω) rece...	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPY-00265	Interferon alpha 2/IFNA2 Protein, Human, Recombinant IFNAB,干扰素,IFNA2B,IFN-alphaA,INFA2,interferon, alpha...	Human	P. pastoris (Yeast)
	Interferon alpha 2/IFNA2 Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 19.3 kDa and the accession number is P01563.1.
TMPY-02634	IFNAR1 Protein, Human, Recombinant (hFc) interferon (α, β and Ω) receptor 1,IFNBR,A...	Human	HEK293 Cells
	IFNAR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 74 kDa and the accession number is P17181-1.
TMPY-04578	Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His) Interferon α1,IFN-alphaD,IFN-αD,IFN-α,interfero...	Human	P. pastoris (Yeast)
	Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 20.8 kDa and the accession number is L0N195.
TMPY-00638	Interferon alpha B/IFNA8 Protein, Human, Recombinant (His) IFN-αB,IFN-alphaB,interferon, α8,Interferon	Human	HEK293 Cells
	Interferon alpha B/IFNA8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.9 kDa and the accession number is A0A7R8C381.
TMPY-02515	Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc) IFN-alphaJ,干扰素,IFNA-J,IFN-αJ,interferon, alpha 7,	Human	HEK293 Cells
	Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P01567.
TMPY-02566	Interferon alpha 4/IFNA4 Protein, Human, Recombinant (His) 干扰素,interferon, α4,MGC142200,interferon, a...	Human	Baculovirus Insect Cells
	Interferon alpha 4/IFNA4 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20.7 kDa and the accession number is P05014.
TMPJ-00331	IFNAR1 Protein, Rhesus macaque, Recombinant (His) IFN-al,CRF2-1,IFN-alpha/beta receptor 1,human interferon...	Rhesus	HEK293 Cells
	Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphory...
TMPH-01549	Interferon epsilon/IFNE Protein, Human, Recombinant (His)	Human	E. coli
	Type I interferon required for maintaining basal levels of IFN-regulated genes, including 2'-5'-oligoadenylate synthetase, IRF7 and ISG15, in the female reproductive tract. Directly mediates protection against viral and bacterial genital infections.
TMPH-01550	Interferon kappa/IFNK Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon-stimulated response element signaling pathway. It is able to directly modulate cytokine release from monocytes and dendritic cells. Binds heparin.
TMPY-00096	Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant interferon, alpha 2,interferon, α2,干扰素,	Rhesus	P. pastoris (Yeast)
	Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant is expressed in yeast. The predicted molecular weight is 19.5 kDa and the accession number is B6CK11.
TMPY-03648	Interferon alpha B/IFNA8 Protein, Human, Recombinant IFN-αB,IFN-alphaB,interferon, alpha 8,Interfero...	Human	HEK293 Cells
	Interferon alpha B/IFNA8 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38 kDa and the accession number is A0A7R8C381.
TMPH-00468	Interferon-inducible MxA protein Protein, Danio rerio, Recombinant (His)	Danio rerio (Zebrafish)	E. coli
	Interferon-inducible MxA protein Protein, Danio rerio, Recombinant (His) is expressed in E. coli.
TMPY-04841	Interferon alpha 7/IFNA7 Protein, Human, Recombinant (His) interferon, alpha 7,interferon, α7,IFN-αJ,...	Human	P. pastoris (Yeast)
	Interferon alpha 7/IFNA7 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 21 kDa and the accession number is A0A7R8C383.
TMPH-00276	Interferon alpha-G/IFNAG Protein, Bovine, Recombinant (His & SUMO)	Bovine	E. coli
	Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Interferon alpha-G/IFNAG Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.2 kDa and the accession number is P49877.
TMPY-02661	Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant (hFc) 干扰素,Ifa2,interferon, alpha 2,interferon, α...	Mouse	HEK293 Cells
	Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.8 kDa and the accession number is P01573.
TMPY-02865	Interferon alpha 1/IFNA1 Protein, Rat, Recombinant (His) interferon, alpha 1,Interferon α1,inte...	Rat	HEK293 Cells
	Interferon alpha 1/IFNA1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.9 kDa and the accession number is P05011.
TMPY-03815	Interferon alpha 14/IFNA14 Protein, Mouse, Recombinant (His) interferon, alpha 14,OTTMUSG00000007662,干扰素,int...	Mouse	HEK293 Cells
	Interferon alpha 14/IFNA14 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.5 kDa and the accession number is Q810G3.
TMPY-04634	Interferon alpha 1/IFNA1 Protein, Mouse, Recombinant (His) Ifa1,Interferon α1,interferon, α1,干扰素,...	Mouse	P. pastoris (Yeast)
	Interferon alpha 1/IFNA1 Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 20.5 kDa and the accession number is A0A7R8GV68.
TMPY-03735	Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (His) Interferon α2/IFNA2,interferon, α2,int...	Rhesus	HEK293 Cells
	Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21 kDa and the accession number is B6CK11.
TMPY-03027	Interferon alpha 4/IFNA4 Protein, Rat, Recombinant (hFc) IFNA4,interferon, α4,interferon, alpha 4,干...	Rat	HEK293 Cells
	Interferon alpha 4/IFNA4 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.5 kDa and the accession number is D3ZFH0.
TMPY-02743	Interferon alpha 1/IFNA1 Protein, Rat, Recombinant (hFc) Interferon α1,干扰素,interferon, α1,inter...	Rat	HEK293 Cells
	Interferon alpha 1/IFNA1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.4 kDa and the accession number is P05011.
TMPH-01545	Interferon alpha 16/IFNA16 Protein, Human, Recombinant (His)	Human	E. coli
	Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Interferon alpha 16/IFNA16 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.4 kDa and the accession number is P05015.
TMPH-01546	Interferon alpha 17/IFNA17 Protein, Human, Recombinant (His)	Human	E. coli
	Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Interferon alpha 17/IFNA17 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.3 kDa and the accession number is P01571.
TMPY-00829	Interferon alpha 4/IFNA4 Protein, Human, Recombinant (hFc) interferon, α4,IFN-α4a,干扰素,interferon, alp...	Human	HEK293 Cells
	Interferon alpha 4/IFNA4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46 kDa and the accession number is P05014.
TMPY-04855	interferon alpha 5/IFNA5 Protein, Human, Recombinant (His) leIF G,IFN-alpha,interferon-α,INA5,IFN-alphaG,IFN-α...	Human	P. pastoris (Yeast)
	interferon alpha 5/IFNA5 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 21.1 kDa and the accession number is A0A7R8C382.
TMPY-02346	Interferon alpha 4/IFNA4 Protein, Mouse, Recombinant (hFc) RP23-139P14.30-001,干扰素,interferon, alpha 4,inte...	Mouse	HEK293 Cells
	Interferon alpha 4/IFNA4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.2 kD and the accession number is P07351.
TMPH-01547	Interferon alpha 21/IFNA21 Protein, Human, Recombinant (His)	Human	E. coli
	Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
TMPY-06407	Interferon alpha 2/IFNA2 Protein, Human, Recombinant (hFc) IFN-αA,INFA2,干扰素,Interferon α2,IFNA2B,interfero...	Human	HEK293 Cells
	Interferon alpha 2/IFNA2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.29 kDa and the accession number is P01563-1.
TMPY-04664	Interferon alpha 4/IFNA4 Protein, Cynomolgus, Recombinant (mFc) IFNA4,干扰素,interferon, alpha 4,interferon, ...	Cynomolgus	HEK293 Cells
	Interferon alpha 4/IFNA4 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 45.6 kDa.
TMPY-03637	Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (His) Interferon α-B,interferon, alpha 8,int...	Cynomolgus	HEK293 Cells
	Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43 kDa and the accession number is G7PS89.
TMPY-03620	Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (mFc) Interferon α-B,interferon, alpha 8,int...	Cynomolgus	HEK293 Cells
	Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46 kDa and the accession number is G7PS89.
TMPY-03355	interferon alpha 5/IFNA5 Protein, Mouse, Recombinant (hFc) interferon, α5,interferon, alpha 5,IFNA5,<...	Mouse	HEK293 Cells
	interferon alpha 5/IFNA5 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46 kDa and the accession number is Q810G2.
TMPY-02526	interferon alpha 5/IFNA5 Protein, Mouse, Recombinant (His) IFNA5,Ifa5,interferon-α,干扰素,interferon, al...	Mouse	HEK293 Cells
	interferon alpha 5/IFNA5 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is Q810G2.
TMPY-02516	Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc) interferon, α10,interferon, alpha 10,IFN-a...	Human	HEK293 Cells
	Interferon alpha-10 (IFNA10) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogen...
TMPY-03892	Interferon alpha 4/IFNA4 Protein, Mouse, Recombinant (His) MGC143607,RP23-139P14.30-001,干扰素,Ifa4,interferon, α...	Mouse	HEK293 Cells
	Interferon alpha 4/IFNA4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.2 kDa and the accession number is P07351.
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重组蛋白

IFN-beta Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00831

Species: Human

Expression System: HEK293 Cells

IFN-beta Protein, Human, Recombinant

Cat.No: TMPY-03145

Species: Human

Expression System: CHO Cells

IFN-beta Protein, Mouse, Recombinant

Cat.No: TMPY-03467

Species: Mouse

Expression System: HEK293 Cells

IFNAR1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02647

Species: Human

Expression System: HEK293 Cells

IFNAR2 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-04799

Species: Human

Expression System: HEK293 Cells

IFN-beta Protein, Rhesus, Recombinant (mFc)

Cat.No: TMPY-03828

Species: Rhesus

Expression System: HEK293 Cells

IFNAR1 Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-04254

Species: Rhesus

Expression System: HEK293 Cells

IFNAR1 Protein, Rhesus, Recombinant (hFc)

Cat.No: TMPY-03829

Species: Rhesus

Expression System: HEK293 Cells

IFNAR2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-00139

Species: Cynomolgus

Expression System: HEK293 Cells

IFNAR1 Protein, Rhesus, Recombinant

Cat.No: TMPY-03927

Species: Rhesus

Expression System: HEK293 Cells

IFN-beta Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02456

Species: Mouse

Expression System: HEK293 Cells

IFNAR1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01489

Species: Mouse

Expression System: HEK293 Cells

Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant

Cat.No: TMPY-00007

Species: Mouse

Expression System: P. pastoris (Yeast)

IFNAR2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01640

Species: Human

Expression System: HEK293 Cells

IFNAR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01642

Species: Human

Expression System: HEK293 Cells

Interferon alpha 2/IFNA2 Protein, Human, Recombinant

Cat.No: TMPY-00265

Species: Human

Expression System: P. pastoris (Yeast)

IFNAR1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02634

Species: Human

Expression System: HEK293 Cells

Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04578

Species: Human

Expression System: P. pastoris (Yeast)

Interferon alpha B/IFNA8 Protein, Human, Recombinant (His)

Cat.No: TMPY-00638

Species: Human

Expression System: HEK293 Cells

Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02515

Species: Human

Expression System: HEK293 Cells

Interferon alpha 4/IFNA4 Protein, Human, Recombinant (His)

Cat.No: TMPY-02566

Species: Human

Expression System: Baculovirus Insect Cells

IFNAR1 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPJ-00331

Species: Rhesus

Expression System: HEK293 Cells

Interferon epsilon/IFNE Protein, Human, Recombinant (His)

Cat.No: TMPH-01549

Species: Human

Expression System: E. coli

Interferon kappa/IFNK Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01550

Species: Human

Expression System: E. coli

Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant

Cat.No: TMPY-00096

Species: Rhesus

Expression System: P. pastoris (Yeast)

Interferon alpha B/IFNA8 Protein, Human, Recombinant

Cat.No: TMPY-03648

Species: Human

Expression System: HEK293 Cells

Interferon-inducible MxA protein Protein, Danio rerio, Recombinant (His)

Cat.No: TMPH-00468

Species: Danio rerio (Zebrafish)

Expression System: E. coli

Interferon alpha 7/IFNA7 Protein, Human, Recombinant (His)

Cat.No: TMPY-04841

Species: Human

Expression System: P. pastoris (Yeast)

Interferon alpha-G/IFNAG Protein, Bovine, Recombinant (His & SUMO)

Cat.No: TMPH-00276

Species: Bovine

Expression System: E. coli

Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02661

Species: Mouse

Expression System: HEK293 Cells

Interferon alpha 1/IFNA1 Protein, Rat, Recombinant (His)

Cat.No: TMPY-02865

Species: Rat

Expression System: HEK293 Cells

Interferon alpha 14/IFNA14 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03815

Species: Mouse

Expression System: HEK293 Cells

Interferon alpha 1/IFNA1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04634

Species: Mouse

Expression System: P. pastoris (Yeast)

Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-03735

Species: Rhesus

Expression System: HEK293 Cells

Interferon alpha 4/IFNA4 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-03027

Species: Rat

Expression System: HEK293 Cells

Interferon alpha 1/IFNA1 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-02743

Species: Rat

Expression System: HEK293 Cells

Interferon alpha 16/IFNA16 Protein, Human, Recombinant (His)

Cat.No: TMPH-01545

Species: Human

Expression System: E. coli

Interferon alpha 17/IFNA17 Protein, Human, Recombinant (His)

Cat.No: TMPH-01546

Species: Human

Expression System: E. coli

Interferon alpha 4/IFNA4 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00829

Species: Human

Expression System: HEK293 Cells

interferon alpha 5/IFNA5 Protein, Human, Recombinant (His)

Cat.No: TMPY-04855

Species: Human

Expression System: P. pastoris (Yeast)

Interferon alpha 4/IFNA4 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02346

Species: Mouse

Expression System: HEK293 Cells

Interferon alpha 21/IFNA21 Protein, Human, Recombinant (His)

Cat.No: TMPH-01547

Species: Human

Expression System: E. coli

Interferon alpha 2/IFNA2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06407

Species: Human

Expression System: HEK293 Cells

Interferon alpha 4/IFNA4 Protein, Cynomolgus, Recombinant (mFc)

Cat.No: TMPY-04664

Species: Cynomolgus

Expression System: HEK293 Cells

Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-03637

Species: Cynomolgus

Expression System: HEK293 Cells

Interferon alpha B/IFNA8 Protein, Cynomolgus, Recombinant (mFc)

Cat.No: TMPY-03620

Species: Cynomolgus

Expression System: HEK293 Cells

interferon alpha 5/IFNA5 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03355

Species: Mouse

Expression System: HEK293 Cells

interferon alpha 5/IFNA5 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02526

Species: Mouse

Expression System: HEK293 Cells

Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02516

Species: Human

Expression System: HEK293 Cells

Interferon alpha 4/IFNA4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03892

Species: Mouse

Expression System: HEK293 Cells

--------- 更多 ---------

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